Title: Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma (ACADIA)
Brief Description: Comparing Albuterol v. Albuterol + Budesonide
Sponsor: AstraZeneca
PI: Sankaran Krishnan
https://clinicaltrials.gov/study/NCT06307665
Title: A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma (HORIZON)
Brief Description: Biologic for younger kids with severe uncontrolled asthma
Sponsor: AstraZeneca
PI: Sankaran Krishnan
https://clinicaltrials.gov/study/NCT06023589
Title: American Lung Association (ALA) Lung Health Cohort
Brief Description: Observational study for healthy adults
Sponsor: American Lung Association
PI: Allen Dozor
https://clinicaltrials.gov/study/NCT04543461
Title: A Phase 1 Study of Inhaled KB407, a Replication-Defective, Non-Integrating Vector Expressing Human Cystic Fibrosis Transmembrane Conductance Regulator, for the Treatment of Cystic Fibrosis
Brief Description: New inhaled CFTR (HSV-1)-derived vector for CF
Sponsor: Krystal Biotech
PI: John Welter
https://clinicaltrials.gov/study/NCT05504837
Title: Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study (STOP360AG)
Brief Description: 1 IV Antibiotic v. 2 IV Antibiotics for treatment of Pulmonary Exacerbation with Pseudomonas
Sponsor: Cystic Fibrosis Foundation
PI: Allen Dozor
https://clinicaltrials.gov/study/NCT05548283
Title: A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators
Brief Description: Observational Study For People With CF Not Taking Modulators
Sponsor: Cystic Fibrosis Foundation
PI: John Welter
https://clinicaltrials.gov/study/NCT06504589
Title: A Phase III, Randomised, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of BI 1291583 2.5 mg Administered Once Daily for up to 76 Weeks in Patients With Bronchiectasis (The AIRTIVITY® Study)
Brief Description: New Medicine for both CF and Non-CF Bronchiectasis
Sponsor: Boehringer Ingelheim
PI: John Welter
https://clinicaltrials.gov/study/NCT06872892
Title: A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants
Brief Description: Comparing New Generation Prevnar Vaccine to Standard Prevnar 20
Sponsor: Pfizer
PI: Sheila Nolan
https://clinicaltrials.gov/study/NCT05609630
Title: Study of Oral Upadacitinib and Subcutaneous/ Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis. (SELECT-sJIA)
Brief Description: Comparing Two Biologics for Systemic Juvenile Idiopathic Arthritis
Sponsor: AbbVie
PI: Christine Hom
https://clinicaltrials.gov/study/NCT05609630
Title: A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab (KnaPsAck)
Brief Description: Comparing Two Biologics for Juvenile Psoriatic Arthritis
Sponsor: AbbVie
PI: Christine Hom
https://clinicaltrials.gov/study/NCT06100744
Title: A Phase III, Randomized, Double-blind, Parallel-group, Placebo Controlled Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of IV Anifrolumab in Pediatric Participants 5 to < 18 Years of Age With Moderate to Severe Active Systemic Lupus Erythematosus (SLE) While on Background Standard of Care Therapy
Brief Description: IV Drug for Pediatric Systemic Lupus Erythematosus (SLE)
Sponsor: AstraZeneca
PI: Christine Hom
https://clinicaltrials.gov/study/NCT05835310
Title: A Phase 2 Basket Study of Vosoritide in Children With Turner Syndrome, SHOX Deficiency and Noonan Syndrome With an Inadequate Response to Human Growth Hormone
Brief Description: Comparing Two Types of Growth Hormone for Children with Noonan Syndrome
Sponsor: BioMarin Pharmaceutical
PI: Shilpa Mehta
https://clinicaltrials.gov/study/NCT06668805